The Hilton is on the monorail so whether you stay there or not it should be easy to get to. My husband liked the hotel but that was back when the Star Trek Experience was there. Sorry I don't have any recent info for there, it was last year.
The Hilton is off the strip though. I prefer to stay on the strip or at the Hard Rock if we go off strip.
There is a lot of fun to be had in Vegas, just do a little research and see what interests you! I like to go by the half price ticket booths, just to see what's available. Keep in mind it's not always half off but usually a bargain none the less!